Crimson Heads are created by a similar process to the Lickers and have similar attributes, but the mutations are completely separate. A Crimson Head will never evolve into a Licker, and the "Suspended" (or Regis Licker as it's incorrectly known) is not an actual Licker, it's a freak mutation. Outbreak's boss enemies were originally meant to be freak mutants such as the Giant Leech, Two-Headed Zombie Dog, Megalodon Neptune and so on.
Very little of the infection actually spread from the mansion. Traces of the virus leaked into the sewer from the mansion (the mansion, hospital and laboratories are all connected via the sewer system, which is in turn connected to the underground carrying-out tunnels) and infected a few people within the vicinity, but the infection wouldn't have spread. The cause of the zombies which appeared in August came from the leak caused by Birkin at the abandoned plant, and these ones began to spread very slowly. It was the attack on Birkin on September 23 that caused a huge leak and was ultimately responsible for the city's destruction, which was made worse by the fact that most of Raccoon City was in one place at the time: the stadium. It became a zombie domino effect at that point.
It's not impossible but it is very, very dumb if you try to explain it away in the plot, in my opinion. It worked in the BH1 remake, it wouldn't work with any other visit to Raccoon City since we've seen enough of it already and they have refused to use Crimson Heads. It would seem tacked on at best. The Crimson Heads in Umbrella's End are there because the strain was most likely sent there. Research in Raccoon City was focused on Birkin's refined strain that created Lickers, Tyrants and Hunters, while the mutant strain was shipped elsewhere to be cultivated for, presumably, mass-production (which is what the base in Russia was explicitly for). Since Arklay (according to BH1 remake) focused heavily on the Crimson Heads and initially discovered them, samples of the mutant strain were still there, which is why it spread when the Queen Leech attacked.
The mutant strain is however purchased from Umbrella and used by Javier to create the faster and stronger "Javier Zombies" in Darkside Chronicles. These weren't true Crimson Heads apparently since their state of suspended animation was artificially induced. Actually receiving damage seems to make the mutation more aggressive, which makes sense since the V-ACT process reconstructs tissue.
EDIT: Of course I'm talking from the perspective of a new game based in Raccoon City, rather than a remake. It could work in the latter but good luck trying get even remotely the same quality as the BH1 remake. The time for remakes of any of the older games has long since passed and nothing good will come out of remaking them now.





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