Leon S. Kennedy
An agent who belongs to a secret military agency under the direct control of the United States President. He infiltrates the field to investigate B.O.W.s which flowed through the Eastern Slav Republic's anti-government forces. He is a witty individual who is calm and composed.
A key member of the anti-government forces in the Eastern Slav Republic. A former elementary school teacher. He captured Leon, who had infiltrated, as a hostage, but unintentionally works together with Leon. He is a reliable man if made an ally. His real name is Alexander Kozachenko.
A mysterious woman who has a connection with Leon. She visits the Eastern Slav Republic as a special investigator from the United Nations counter bioterrorism organization, the BSAA.
A member of the anti-government forces. He is Americanized under the influence of movies, music and fast food. Contrary to his appearance, he is a good-natured young man who adores his friends.
A leader of the anti-government force's senior congress. He plans a mission to invade the Executive Office of the President, but his physical strength is weakened and he needs the help of Buddy and others.
The Eastern Slav Republic President. Backed by financial power that she accumulated in business, she stepped forward in politics. She became the republic's first female President. She advocates the annihilation of terrorism.
A woman of the U.S. Government. She gives Leon instructions through a PDA. She tells Leon of his mission's cancellation when he goes to the Eastern Slav Republic.